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Studies actively recruiting Heading link

Mood and Exercise Training Study for Multiple Sclerosis

This study examines the effectiveness of exercise training for improving depression and other outcomes among persons with MS who have major depressive disorder. We are comparing two remotely delivered exercise training programs for improving depressive symptoms, cognition, and quality of life among persons with MS who have major depressive disorder. We are seeking participants who:

  1. are between 18-64 years of age,
  2. have an MS diagnosis,
  3. have major depressive disorder,
  4. have Internet and email access,
  5. are currently physically inactive,
  6. are willing to complete training,
  7. are ambulatory, and
  8. use English as a primary language.

Visit our website or contact Alison at (312) 415-1790 or

Healthy Aging through LifesTyle in Multiple Sclerosis – Exercise Trial

This is the first study examining the feasibility and efficacy of a 16-week remotely delivered, exercise training program for adults (50+ years) with MS who have cognitive and walking impairment. We are examining if this targeted, evidence-based exercise program will produce improvements in cognition, mobility, physical activity, vascular function, and quality of life among adults (50+ years) with MS. We are recruiting participants who:

  1. are 50 years of age or older,
  2. have an MS diagnosis,
  3. use English as a primary language,
  4. have Internet and email access, and
  5. have mild-to-moderate cognitive and walking impairment.

Contact Peixuan at (312) 355-0383 or

Physical Activity, Cerebral Pulsatile Stress and Serum Neurofilament Light Chain as an Objective, Quantifiable Biomarker of Neuroaxonal Injury in Multiple Sclerosis

This pilot study examines if physical activity is associated with a blood biomarker of MS disease severity (neurofilament light chain), cognitive function, and vascular health in people with MS. Neurofilament light chain is a blood biomarker of damage in the central nervous system caused by MS. This research will provide the basis for future research examining if physical activity can reverse the effects on MS on brain structure and cellular outcomes. We are currently recruiting participants with or without MS who:

  1. age between 18-54 years,
  2. no relapse within the last 30 days,
  3. ability to walk unassisted, and
  4. ability to read, write, and speak English.

For more information, contact Trevor at (312) 355-0383 or